Once I played a "gun-expert" type of character and collected every single weapon in game in the car's trunk. Fun times.
On lady characters, I tend to carry cosmetics case, mirror shades and necklace and a few handy bottles of liquor etc. "small items" that ladies tend to carry around
When I haul around NPC's, I like to give them items that "suit" them, like someone mentioned, "repair items", old junk and gadgets to Vic, drugs and alcohol to Myron, healing powder and selection of melee weaponry for Sulik etc.
And this is bit of a ritual for me, always carrying a loaded handgun (preferably extended desert eagle), knife, rope, dynamite, lighter, bunch of flares and few bottles of nuka cola - the ultimate survival kit.
Too bad the eating / drinking / sleeping stuff isn't implemented in Fallout 2, I don't like to carry around the foodstuff for nothing

Though, sometimes after completing some "goal", it's fun to throw up a party in some bar and give tons of beer and iguana bits to every patron. The addiction system is a bit cumbersome as well, would be fun to play total druggie who flips out at people if not able to get the daily dose.